by Jim West (please share and cite)
This is literary criticism, about virology.
Virology's trap is complexity. Let's avoid it. Comments are welcome.
Dr. Mercola's declares,
Overview of my critique
Five irrelevant studies
Mercola presents five studies to support his declaration of Covid-19 virus existence.
The five studies are irrelevant because they are dependent studies. They use a genetic definition provided by an initial discovery study in order to detect the "virus",..
Only a discovery study claims proof of "virus" existence and sends samples and data to a central catalogue, (ATCC).
Dependent studies begin by declaring faith in the discovery study.
Dependent studies use the definition at ATCC to: Find the "virus", to seek additional "virus" properties such as structural variants, to seek epidemiological data, and to develop lab products and procedures.
For a valid argument, Mercola et al would have to present a valid discovery study. But amazingly, he only presents five dependent studies.
Mercola presents a video by his contributor, Jeremy Hammond.
Mercola begins with assertions.
While some still claim SARS-CoV-2 doesn’t actually exist, this seems to fly in the face of several well-established facts. The virus has actually been photomicrographed,1,2 whole-genome sequences of the various strains are available,3,4 and with the appropriate credentials anyone can obtain the live virus to conduct research.
While I am absolutely no fan of the U.S. Centers for Disease Control and Prevention, they do grow the virus in cell culture to ensure widespread availability for researchers who want to study it.5 Examples of research where you need the actual virus include antiviral research, vaccine development, virus stability research and pathogenesis research.6
Mercola describes the "root" problem as “confusion” over the meaning of the two key words, “isolated” and “purified”.
What’s the Confusion?
At least part of the confusion appears to be rooted in how the term “isolated” is defined.
Some insist a virus is not isolated unless it’s also purified, while others say a virus doesn’t have to be purified in order to be “isolated.”
Mercola does not tell his readers that the words "isolated" and "purified" have bizarre meanings in virology.. He doesn't offer any definitions. Yet, his article uses "isolated" 35 times, and "purified" 1 time
Confusion is guaranteed.
Mercola brings in Steve Kirsch.
Generally, Steve Kirsch's view of the scientific method borders is absurd, to say it nicely. I have debated him and he ran. See details.
In Mercola's article, he claims to have asked several experts about this, noting that all, including Dr. Robert Malone and Dr. Li-Meng Yan, say that the virus has indeed been isolated. “So, it has been ‘isolated’ according to their belief in what the term means,” Kirsch writes, adding:7
“Others interpret the term differently and would claim the virus hasn’t been isolated. In fact, according to their definition, no virus in history has ever been isolated. That’s important to know. They use that as justification for their belief that there is no virus here since viruses don’t exist at all."
Kirsch is a circular thinker -- the "opinions of people" he "trusts," starting with "his readers".
"I rely on expert opinions of people who I trust for certain issues like whether or not the virus has been “isolated”.
When Kirsch asked his readers for input, one pointed out:8
“The real question is... has it been isolated from a HUMAN subject w/o passing it through (say) Monkey Kidney Cells? Because there is plenty of evidence out there that says it hasn't been isolated directly (no intermediaries) from a HUMAN subject.”
Irrelevant study #1
Kirsch introduces this study with more circular thinking: "Hazan verified that the... virus... from the ATCC [catalogue]... matched what she found in people who have the virus."
According to Kirsch, the scientists he spoke with did not agree that this was a concern, and “Sabine Hazan verified that the sequence of the virus obtained from ATCC (the American Type Culture Collection, a global resource center for reference microorganisms) matched exactly what she found in people who have the virus.”9
As noted in Hazan’s paper, “Detection of SARS-CoV-2 From Patient Fecal Samples by Whole Genome Sequencing”:10
Hazan found positive "samples" by matching her found "virus" with the ATTC "virus". She did not prove existence of the virus. She is promoting a lab technique called NGS (Next Generation Sequencing). She proved that she can successfully use NGS with a reference sample from ATCC.
“Study participants underwent testing for SARS-CoV-2 from fecal samples by whole genome enrichment NGS [next-generation sequencing] (n = 14), and RT-PCR nasopharyngeal swab analysis (n = 12).
The concordance of SARS-CoV-2 detection by enrichment NGS from stools with RT-PCR nasopharyngeal analysis was 100%. Unique variants were identified in four patients, with a total of 33 different mutations among those in which SARS-CoV-2 was detected by whole genome enrichment NGS.”
With nothing in hand, Mercola offers compromise.
Germ Theory and Terrain Theory Both Have Merit
As noted by independent journalist and political analyst Jeremy Hammond in a March 2021 interview,11 the claim that SARS-CoV-2 has never been isolated and actually doesn’t exist at all is perhaps one of the most counterproductive arguments of the health freedom movement.
Mercola cannot explain how the no-virus argument is “counterproductive”.
He resorts to conflating apples and oranges ("no virus" and "5G radiation alone").
By insisting that there is no virus, and that COVID-19 is caused by things like 5G radiation alone, allows [sic] the mainstream media to dismiss entirely legitimate concerns…
Like Hammond, I believe the pathogenesis of COVID-19 involves both germ theory and terrain theory, not just one or the other. “SARS-CoV-2 infection is an insufficient but necessary factor in the pathogenesis of COVID-19,” Hammond says, adding that “the virus is constantly being isolated and whole genome sequenced by scientists all over the world.”12
That said, environmental factors can clearly play a role in that they can make you more or less predisposed to severe infection when you encounter this virus. This includes EMFs, toxins like glyphosate, previous vaccine injuries and much more.
Mercola paints himself as a generous compromiser. This allows omnipresent "virus" hype to continue dominating environmental concerns.
Hammond argues that the “COVID-19 pandemic should be a wake-up call to the human population, and especially the populations of developed countries, about the need to focus on natural means of maintaining good health and living in greater harmony with our natural environment.”
Indeed. And, as Hammond points out, pathogenic challenge is absolutely necessary for general good health and strong immunity. When we shield ourselves too much from everyday pathogens, we make ourselves vulnerable to chronic diseases instead.
Irrelevant study #2
SARS-CoV-2 Genome Sequencing From Italy
As for whether SARS-CoV-2 has been isolated and exists as a viral entity, the answer appears to be yes. For example, an Italian paper13 published in the Journal of Virology, dated May 18, 2020, detailed the isolation and full-length genome of the virus taken from COVID-19 patients in Italy:
This is a dependent study, as indicated by its examination of swab mucus already found "positive for SARS-CoV-2" via a test designed from the discovery study's "virus" at ATCC.
The study detects RNA fragments. It is not trying to prove these fragments to be a virus. It assumes so -- and uses a test that matches the RNA fragments with the "virus" at ATCC.
Mercola quotes the irrelevant tech:
“At the beginning of March 2020, the first nasopharyngeal swabs positive for SARS-CoV-2 started to be detected in the Northern Eastern Region of Friuli-Venezia Giulia... Swab contents were seeded on Vero E6 cells and monitored for cytopathic effect and by an RT-PCR protocol using primers for the N region.
Cell culture supernatants from passage 1 (P1) of four isolates were collected, and RNA was extracted with QIAamp viral RNA minikit (Qiagen) and quantified with an in vitro-transcribed RNA standard ... The quantity and quality of the RNA were assessed ... For each sample, 100 ng of total RNA was processed using Zymo-Seq RiboFree ribosomal depletion library preparation kit (Zymo Research).
All the obtained libraries passed quality check and were quantified before being pooled at equimolar concentration and sequenced ... Sequenced reads that passed the quality check (Phred score ≥30) were adaptor and quality trimmed, and the remaining reads were assembled de novo using Megahit (v.1.2.9) with default parameter settings.
Megahit generated in all cases 7 contigs with more than 1,000 bp and 100× coverage; all of these assembled contigs were compared (using BLASTn) against the entire nonredundant (nr) nucleotide and protein databases.
In all cases the longest and more covered contigs were identified as MT019532.1,14 ‘Severe acute respiratory syndrome coronavirus 2 isolate BetaCoV/Wuhan/IPBCAMS-WH-04/2019, complete genome,’ with 99% identity and 0 gaps.
The longer sequences were named hCoV-19/Italy/FVG/ICGEB_S1, _S5, _S8, and _S9 and were deposited in GISAID... Sequence analysis showed an uneven coverage along the SARS-CoV-2 genome, with an average range from 126 to 7,576 reads and a mean coverage per sample of 1,169×... Phylogenetic trees were inferred using the maximum likelihood method...
The first sequences deposited in GISAID (EPI_ISL_410545 and EPI_ISL_410546) were collected in Rome from a Chinese tourist from Hubei province who got infected before visiting Italy, and another one (EPI_ISL_412974) was from a test-positive Italian citizen returning from China.
Only two sequences were reported from the Lombardy cluster (EPI_ISL_412973 and EPI_ISL_413489). In this report four additional sequences from cases epidemiologically linked to northern Italy have been examined ... Sequence analysis showed a good coverage along the SARS-CoV-2 genome for all four isolates.
Based on the marker variant S D614G, all four sequences grouped in the Bavarian rooted subclade G, which is dominant in Europe, including the sequence from Lombardy, but distinct from the three sequences mentioned above originating directly from China.
Intriguingly, the new isolates were more closely related to EPI_ISL_412973, while EPI_ISL_413489 was more distant. No evidence could be found for the putative 382-nucleotide (nt) deletion in ORF8 detected in Singapore, which has been proposed to indicate an attenuated phenotype.
Irrelevant study #3
SARS-CoV-2 Genome Sequencing From Germany
Similarly, the complete genome sequence of the virus taken from a German woman has been published, this one in the journal Microbiology Resource Announcements, in June 2020.
This is a dependent study, as indicated by, "swab sample... tested positive" and "already logged in the gene bank" [ATCC].
Here, an oropharyngeal swab sample from a female patient who tested positive but had no symptoms at the time of the test was used to isolate the strain.15 Table 1 in the paper compares the nucleotide variants found in the sampled virus and those of a reference strain already logged in the gene bank.
Irrelevant study #4
Another paper16 in Annals of Internal Medicine, published in August 2020, isolated the virus from ocular (eye) secretions of an Italian COVID patient:17
This is a dependent study, as indicated by, "Infection with SARS-CoV-2 was confirmed" [with a PCR test matching the discovery study's "virus" genetic code at ATTC]..
The discovery study's "virus" at ATTC is never challenged during an epidemic (if ever challenged). Example: A gross lab error, enshrined for over seven decades, but never challenged.
“The patient, a 65-year-old woman, travelled from Wuhan, China, to Italy on 23 January 2020 and was admitted on 29 January 2020, 1 day after symptom onset. At admission to the high isolation unit ... she presented with nonproductive cough, sore throat, coryza, and bilateral conjunctivitis. She had no fever until day 4, when fever (38 °C), nausea, and vomiting began.
Infection with SARS-CoV-2 was confirmed by performing real-time reverse transcription polymerase chain reaction (RT-PCR) assay on sputum samples (cycle threshold value [Ct], 16.1) on the admission day, followed by viral M gene sequencing (GenBank accession number MT008022), and virus isolation on Vero E6 cell line (2019-nCoV/Italy-INMI1).
The full genome sequence was obtained from either clinical sample or culture isolate (GISAID accession numbers EPI_ISL_410545 and EPI_ISL_410546).”
Irrelevant study #5
Genome Sequencing From India and Colombia
SARS-CoV-2 has also been isolated from the urine of a COVID-19 patient.18 A November 2020 paper19 sought to determine “whether various clinical specimens obtained from COVID-19 patients contain the infectious virus,” and found SARS-CoV-2 RNA “in all naso/oropharyngeal swabs and saliva, urine and stool samples collected between Days 8 and 30 of the clinical course.”
This is a dependent study, as indicated by the use of a "specimen from a COVID-19 positive patient" [declared "positive'" via an earlier test based on the ATCC definition].
Viable SARS-CoV-2 was also found in the nasal washes of ferrets that had been inoculated with urine or stool from a COVID-19 patient. The virus has also been isolated by researchers in the U.S.,20 China,21 India,22 Canada,23 Australia,24 Korea25 and Colombia.26 The Colombian paper reads in part:27
“Objective: To describe the isolation and characterization of an early SARS-CoV-2 isolate from the epidemic in Colombia. Materials and methods: A nasopharyngeal specimen from a COVID-19 positive patient was inoculated on different cell lines.
To confirm the presence of SARS-CoV-2 on cultures we used qRT-PCR, indirect immunofluorescence assay, transmission and scanning electron microscopy, and next-generation sequencing.
Results: We determined the isolation of SARS-CoV-2 in Vero-E6 cells by the appearance of the cytopathic effect three days post-infection and confirmed it by the positive results in the qRT-PCR and the immunofluorescence with convalescent serum.
Transmission and scanning electron microscopy images obtained from infected cells showed the presence of structures compatible with SARS-CoV-2. Finally, a complete genome sequence obtained by next-generation sequencing allowed classifying the isolate as B.1.5 lineage.
The evidence presented in this article confirms the first isolation of SARSCoV-2 in Colombia. In addition, it shows that this strain behaves in cell culture in a similar way to that reported in the literature for other isolates and that its genetic composition is consistent with the predominant variant in the world.”
If Virus Exists, Why Aren’t Certain Studies Done?
"Virus" studies never discount obvious contradicting factors such as environmental causation. This elephant in the room indicates that these studies are actually detecting free RNA fragments caused by pollution.
Mercola concludes by leading his readers down a pro-vaccine rabbit hole. His concern for the environment is gone.
As mentioned earlier, the actual virus is needed in order to conduct certain studies.
Now, since the virus does exist, we also ought to be able to conduct studies to assess whether the COVID shots cause antibody dependent enhancement (ADE).
Mercola the Compromising Vaxer -- is why the best argument is “no virus”.
Very strong evidence points to: the COVID-19 vaccine...
1) Killing and maiming over a thousand professional athletes.
2) Raising disease incidence up to 10x according to military data.
3) Funeral home directors finding blood clots in 50% of their cases, and only from the vaccinated.
4) Pediatric clinic nurse finding 10x increase in myocarditis.
5) JAMA study finding an epidemic of myocarditis correlating with the vaccine, and warns that it is under-reporting.
Solution: With the no-virus argument, bogus studies and stories are then immediately recognized. Environmental threats are then efficiently discussed.
Obvious environmental examples:
1) The environmental trigger of COVID-19 epidemics
2) Prenatal ultrasound causation for chorioamnionitis
3) Toxic causation for polio epidemics
4) The epidemic of smart meters
[Mercola's] Sources and References
- 1, 7, 8, 28 Steve Kirsch Substack January 9, 2022
- 2 NPR January 24, 2020
- 3 Gen Bank SARS-CoV-2 isolate, complete genome
- 4 ATCC Coronavirus
- 5, 6 CDC Viral Culturing
- 9, 10 Gut Pathogens 2021; 13(7)
- 11, 12 Jeremy Hammond March 9, 2021
- 13 Journal of Virology May 18, 2020 DOI: 10.1128/JVI.00543-20
- 14 MT019532.1
- 15 Microbiology Resource Announcements June 2020; 9(23): e00520-20
- 16, 17 Annals of Internal Medicine August 4, 2020 DOI: 10.7326/M20-1176
- 18 Emerging Microbes & Infections December 2020; 9(1):991-993
- 19 Clinical Microbiology & Infections November 2020;26(11):1520-1524
- 20 BioRxiv March 7, 2020 DOI: 10.1101/2020.03.02.972935
- 21 CCDC Weekly February 15, 2020 DOI: 10.46234/ccdcw2020.033
- 22 Indian Journal of Medical Research February & March 2020; 151(2 & 3):244-250
- 23 Emerging Infectious Diseases September 2020; 26(9): 2054–2063
- 24 The Medical Journal of Australia July 28, 2021
- 25 Osong Public Health Research Perspectives February 2020; 11(1): 3-7
- 26, 27 Biomedica October 30, 2020; 40(Supl. 2):148-158
Dr. Mercola's Censored Library
As most of you know, I've been forced to remove 25 years of free health information from my website under threats of the technocratic elite.
By popular demand, I am pleased to share with you an exciting update — my entire Censored Library has finally returned! Through Substack, an information sharing platform, I am once again able to share with you all the valuable research I have gathered through the years.